Factory Provide Veterinary Drug Amphotericin B Powder CAS 1397-89-3
Introduction
Product Name : Amphotericin B
Other name:FUNGIZONE;FUNGIZONE(R);ABELCET;AMBISOME;AMPHOTERCIN B
CAS No.: 1397-89-3
MF: C47H73NO17
Purity :99%
MW:924.08
Melting Point :>170°C
Boiling Point :804.34°C (rough estimate)
Density :1.34 (rough estimate)
Appearance: Yellow Powder
Storage :Sealed in dry,Sealed in dry,Room Temperature
Amphotericin B is a polyene antifungal drug. Fungi that are sensitive to this product include Cryptococcus neoformans, Blastomyces dermatitis, Histoplasma, Coccidioides, Sporothrix, Candida, etc. Some Aspergillus species are resistant to this product; skin and Trichophyton Most of them are resistant. This product has no antimicrobial activity against bacteria, rickettsiae, viruses, etc. The drug concentration achieved by the commonly used therapeutic dose has only bacteriostatic effect on fungi.
Function and Application
Amphotericin B is an antifungal medication that fights infections caused by fungus.
Amphotericin B is used to treat serious, life-threatening fungal infections. It is not for use in treating a minor fungal infection such as a yeast infection of the mouth, esophagus, or vagina.
Amphotericin B may also be used for purposes not listed in this medication guide.
Amphotericin B is a polyene antifungal antibiotic produced by Streptomyces nodosus, with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, thereby causing depolarization of the membrane and altering cell membrane permeability. This leads to leakage of important intracellular components, cell rupture, and eventually cell death. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells.
Indications
Used for visceral or systemic infections caused by Cryptococcus, Coccidioides, Histoplasma capsularis, Blastomyces, Sporothrix, Candida, Mucor, Aspergillus, etc.
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