Ampicillin NEW

Ampicillin: Overview

Definition
Ampicillin is a broad-spectrum β-lactam antibiotic belonging to the penicillin class. It inhibits bacterial cell wall synthesis, effective against both Gram-positive and select Gram-negative bacteria.

Function
Ampicillin demonstrates bactericidal activity against pathogens such as Escherichia coli, Salmonella, Haemophilus influenzae, and Streptococcus species. While susceptible to β-lactamase degradation, it is often combined with β-lactamase inhibitors (e.g., sulbactam) to enhance resistance coverage.

Applications
Commonly used in clinical and hospital settings to treat:

· Respiratory infections (e.g., bronchitis, pneumonia)

· Urinary tract infections

· Gastrointestinal infections (e.g., salmonellosis)

· Meningitis (when caused by susceptible strains)

· Septicemia