Aztreonam
Definition
Aztreonam is a synthetic, monocyclic beta-lactam antibiotic belonging to the monobactam class. It is primarily effective against Gram-negative bacteria, including Pseudomonas species, and is resistant to beta-lactamases.
Function
· Inhibits bacterial cell wall synthesis, leading to bacterial cell lysis and death.
· Specifically targets Gram-negative pathogens, making it effective in treating a range of infections.
Applications
· Pharmaceuticals: Used to treat serious infections caused by Gram-negative bacteria, including urinary tract infections, respiratory infections, and septicemia.
· Hospital Use: Often administered in hospital settings for patients with infections resistant to other antibiotics.
· Biotechnology & Research: Utilized in laboratory settings to study bacterial resistance mechanisms and conduct antibiotic sensitivity tests.