BAPTA tetrasodium
Modify Date: 2025-08-26 08:57:19
 BAPTA tetrasodium structure | Common Name | BAPTA tetrasodium |
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| CAS Number | 126824-24-6 | Molecular Weight | 564.361 |
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| Density | N/A | Boiling Point | 766.6ºC at 760 mmHg |
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| Molecular Formula | C22H20N2Na4O10 | Melting Point | N/A |
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| MSDS | USA | Flash Point | 417.4ºC |
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Use of BAPTA tetrasodium BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3]. |
Properties
Articles1
Spectrum
Names
| Name | 1,2-Bis(2-aminophenoxy)-ethane-N,N,N,N-tetraacetic acid tetrasodium salt |
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| Synonym | More Synonyms |
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BAPTA tetrasodium Biological Activity
| Description | BAPTA tetrasodium is a selective chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca2+ release from intracellular stores or influx via Ca2+-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca2+ chelators[1][2][3]. |
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| Related Catalog | Signaling Pathways >> Metabolic Enzyme/Protease >> Phospholipase Research Areas >> Others |
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| In Vitro | BAPTA (0.3-30 μM; 1 h) can be used for the prevention of [Ca2+]-induced cell damage, but disturbe calcium signalling in isingle differentiated NH15-CA2 neuroblastoma and glioma hybrid cells[3]. BAPTA (0-10 mM) inhibits phospholipase C (PLC) activity in a dose-dependent manner, and is unrelated to Ca2+[2]. |
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| References | [1]. R Y Tsien, et al. New calcium indicators and buffers with high selectivity against magnesium and protons: design, synthesis, and properties of prototype structures. Biochemistry. 1980 May 27;19(11):2396-404. [2]. Roger C Hardie, et al. Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA. Cell Calcium. 2005 Dec;38(6):547-56. [3]. M B Collatz, et al. Intracellular calcium chelator BAPTA protects cells against toxic calcium overload but also alters physiological calcium responses. Cell Calcium |
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Chemical & Physical Properties
| Boiling Point | 766.6ºC at 760 mmHg |
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| Molecular Formula | C22H20N2Na4O10 |
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| Molecular Weight | 564.361 |
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| Flash Point | 417.4ºC |
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| Exact Mass | 564.070862 |
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| PSA | 185.46000 |
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| Storage condition | -20°C |
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MSDS
BAPTA tetrasodium MSDS(Chinese) |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn |
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| Risk Phrases | R20/21/22 |
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| Safety Phrases | S24/25 |
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| RIDADR | NONH for all modes of transport |
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