| Name | Bax inhibitor peptide V5 acetate |
| Description | Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment. |
| In vitro | Bax inhibitor peptide V5 (BIP-V5; 0-50 μM) decreases cell death in STF-cMyc cells but not in SW620 or NCI-H23 cells.[1]. V5 treatment upregulates expression of anti-apoptotic proteins Bcl-2 and XIAP by more than 3- and 11-fold and downregulates expression of apoptosis-inducing proteins Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively[2]. |
| In vivo | Bax inhibitor peptide V5 (BIP-V5; 100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model[2]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Saline : 100 mg/mL (154.6 mM), Heating is recommended. H2O : 100 mg/mL (154.6 mM), Sonication is recommended. DMSO : 100 mg/mL (154.6 mM), Sonication is recommended.
|
| Keywords | Bax inhibitor peptide V-5 acetate | Bax inhibitor peptide V5 acetate | Apoptosis | 579492-81-2 free base | 579492-81-2 |
| Inhibitors Related | Stavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Sodium Molybdate | Sildenafil citrate |
| Related Compound Libraries | Apoptosis Compound Library | Bioactive Compound Library | Peptide Compound Library | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |