| Name | Bay K 8644 |
| Description | Bay K 8644 (SQ 28,873) is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM. |
| In vitro | Bay K 8644 increases resting tension in segments of mesenteric arteries isolated from young and old rats as an agonist of L-type Ca2+ channel[2] |
| In vivo | Bay K 8644 induces small contractions in aortae from Wistar-Kyoto(WKY) rats of 5-week-, 3-month-, 1-year-, 1.5-year-old, which are unaltered with age.[3] |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 1 mg/mL (2.81 mM), Sonication is recommended. DMSO : 83.33 mg/mL (233.88 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble) Ethanol : 35.6 mg/mL (99.92 mM), Sonication is recommended.
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| Keywords | sarcolemmal | L-type calcium channel | L-type | Inhibitor | inhibit | influx | CalciumChannel | Calcium Channel | Ca2+ channels | Ca2+ | Ca channels | BAY-K-8644 | BAY-K8644 | BAY-K 8644 | Bay K-8644 | Bay K8644 | Bay K 8644 | (±)-Bay K 8644 |
| Inhibitors Related | Quadrol | Tricaine methanesulfonate | Nisoldipine | 2,4,6-Tri-tert-butylphenol | Chlorocresol | L-Ascorbic acid | L-Phenylalanine | L-Ascorbic acid sodium salt | 1-Octanol | 2-Nitrobenzoic acid | Magnesium Chloride Hexahydrate | Magnesium sulfate |
| Related Compound Libraries | Reprogramming Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Calcium Channel Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Ion Channel Targeted Library | Anti-Cancer Compound Library | Anti-Hypertension Compound Library |