PRODUCT INFORMATION
| Common Name | Benzenesulfonamide |
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| CAS Number | 98-10-2 | Molecular Weight | 157.19 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 299.1±23.0 °C at 760 mmHg |
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| Molecular Formula | C6H7NO2S | Melting Point | 149-152 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 134.7±22.6 °C |
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| Symbol |  GHS07 | Signal Word | Warning |
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Use of Benzenesulfonamide Benzenesulphonamide (compound 1) is a potent carbonic anhydrase inhibitor. Benzenesulphonamide shows CA II inhibitory activity[1]. |
Properties
Articles41
Spectrum
Names
| Name | Benzenesulfonamide |
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| Synonym | More Synonyms |
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Benzenesulfonamide Biological Activity
| Description | Benzenesulphonamide (compound 1) is a potent carbonic anhydrase inhibitor. Benzenesulphonamide shows CA II inhibitory activity[1]. |
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| Related Catalog | Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase |
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| Target | CA II[1] |
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| References | [1]. Thakur A, et al. QSAR study on benzenesulphonamide carbonic anhydrase inhibitors: topological approach using Balaban index. Bioorg Med Chem. 2004 Feb 15;12(4):789-93. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 299.1±23.0 °C at 760 mmHg |
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| Melting Point | 149-152 °C(lit.) |
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| Molecular Formula | C6H7NO2S |
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| Molecular Weight | 157.19 |
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| Flash Point | 134.7±22.6 °C |
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| Exact Mass | 157.019745 |
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| PSA | 68.54000 |
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| LogP | 0.62 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.584 |
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| Water Solubility | 4.3 g/L (16 ºC) |
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MSDS
Benzenesulfonamide MSDS(Chinese) |
Toxicological Information
CHEMICAL IDENTIFICATIONCHEMICAL NAME : Benzenesulfonamide
CAS REGISTRY NUMBER : 98-10-2
MOLECULAR FORMULA : C6-H7-N-O2-S
HEALTH HAZARD DATAACUTE TOXICITY DATASPECIES OBSERVED : Rodent - rat
REFERENCE : 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1073,1986
SPECIES OBSERVED : Rodent - mouse
REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 19(12),47,1975
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,548,1965
SPECIES OBSERVED : Rodent - rabbit
REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 36(6),19,1971
SPECIES OBSERVED : Rodent - guinea pig
REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 36(6),19,1971 ** OTHER MULTIPLE DOSE TOXICITY DATA **
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 5280 mg/kg/30D-I
REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 51(1),88,1986
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 12180 mg/kg/9W-I
REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 36(6),19,1971
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 636 mg/kg/30W-I
REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 36(6),19,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0266 No. of Facilities: 126 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 2957 (estimated) No. of Female Employees: 1600 (estimated)
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Safety Information
| Symbol |  GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xn:Harmful |
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| Risk Phrases | R22 |
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| Safety Phrases | S36 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | DA9380000 |
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| HS Code | 29350090 |
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Precursor & DownStream
| Precursor 10 | Previous 1/3 Next |
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Customs
| HS Code | 2935009090 |
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| Summary | 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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