| Name | beta-Amyrone |
| Description | beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity. |
| In vitro | beta-Amyrone inhibits α-glucosidase AChE and fungal activity with IC50 values of 25 μM, 23 μM and 8 μg/mL, respectively[1]. In LPS-stimulated J774 cells, beta-Amyrone (2.5, 5, 10 μg/mL) inhibits NO production with an IC50 value of 4.61 μg/mL without obvious effects on cell viability[4]. beta-Amyrone (10 μg/mL) inhibits IL-6, IL-10 levels, and COX-2 expression at the dose of 10 μg/mL[4]. |
| In vivo | In ear phenol-induced edema in Balb C mice, beta-Amyrone (0.1, 0.3, 0.6 mg/kg) inhibits ear edema formation in a dose-related manner[4]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 4.25 mg/mL (10.01 mM), Sonication is recommended.
Ethanol : < 0.1 mg/ml (insoluble)
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| Keywords | β-Amyrone | PPAR | PI3K-Akt | Peroxisome proliferator-activated receptors | obesity | Inhibitor | inhibit | inflammation | infection | Fungal | Cyclooxygenase | COX-2 | COX | CHIKV | beta-Amyrone | beta-Amyron | b-Amyrone | b-Amyron | Anti-inflammatory | antifungal | Antifection | AChR | AChE |
| Inhibitors Related | Calcium Propionate | Dehydroacetic acid sodium | Acetaminophen | Benzyl propionate | Terbinafine hydrochloride | Daidzein | Metronidazole | Sodium formate | Magnesium acetate tetrahydrate | Geraniol | N,N-Dicyclohexylcarbodiimide | Trometamol |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Medicinal and aromatic plants natural product library | Bioactive Compound Library | Anti-Fungal Compound Library | Anti-Viral Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Bioactive Lipid Compound Library | Anti-Cancer Compound Library | Food as Medicine Compound Library |
United States
