PRODUCT INFORMATION
| Common Name | beta-hydroxyethoxyacetic acid |
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| CAS Number | 13382-47-3 | Molecular Weight | 120.10400 |
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| Density | 1.29g/cm3 | Boiling Point | 323.8ºC at 760mmHg |
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| Molecular Formula | C4H8O4 | Melting Point | 44ºC |
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| MSDS | N/A | Flash Point | 147.3ºC |
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Use of beta-hydroxyethoxyacetic acid (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine[1]. |
Names
| Name | 2-(2-hydroxyethoxy)acetic acid |
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| Synonym | More Synonyms |
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beta-hydroxyethoxyacetic acid Biological Activity
| Description | (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine[1]. |
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| Related Catalog | Research Areas >> Others Signaling Pathways >> Others >> Others |
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| In Vitro | (2-Hydroxyethoxy)acetic acid (HEAA) exists in a pH-dependent equilibrium with the cyclic lactone dioxan-2-one, whereby the open-chain form of (2-Hydroxyethoxy)acetic acid is found to be stable under acidic conditions[1]. |
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| In Vivo | The main metabolic pathway of 1,4-Dioxane is oxidized by cytochrome P450 monooxygenase to (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid; HEAA), which is then rapidly excreted in urine[1]. |
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| References | [1]. Elisabeth Eckert, et al. Reliable quantitation of β-hydroxyethoxyacetic acid in human urine by an isotope-dilution GC-MS procedure. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 15;935:80-4. |
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Chemical & Physical Properties
| Density | 1.29g/cm3 |
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| Boiling Point | 323.8ºC at 760mmHg |
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| Melting Point | 44ºC |
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| Molecular Formula | C4H8O4 |
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| Molecular Weight | 120.10400 |
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| Flash Point | 147.3ºC |
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| Exact Mass | 120.04200 |
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| PSA | 66.76000 |
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| Vapour Pressure | 2.01E-05mmHg at 25°C |
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| Index of Refraction | 1.458 |
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Precursor & DownStream
| Precursor 6 | Previous 1/2 Next |
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CAS#:3926-62-3 Sodium chloroacetate
CAS#:107-21-1 Ethylene glycol
CAS#:123-91-1 1,4-Dioxane
CAS#:16024-56-9 2-(2-Methoxyeth...
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| DownStream 1 |
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Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| (2-hydroxy-ethoxy)-acetic acid |
| Acetic acid,2-(2-hydroxyethoxy) |
| (2-Hydroxy-aethoxy)-essigsaeure |
| Glykoloxyessigsaeure |
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