Betaine Anhydrous
CAS No: 107-43-7
Molecular Formula: C₅H₁₁NO₂
Molecular Weight: 117.15 g/mol
1. Product Description
Betaine Anhydrous (also known as Trimethylglycine, TMG) is a naturally occurring quaternary ammonium compound. It appears as a white crystalline powder, is highly soluble in water, and has a mildly sweet taste. It is widely used as a methyl donor in biochemical processes, as a nutritional supplement, and as a feed additive for poultry, swine, and aquaculture.
2. Specifications – Food / Nutraceutical / Pharmaceutical Grade
| Item | Specification / Typical Value | Notes |
|---|
| Appearance | White crystalline powder | Visual |
| Identification | Positive for betaine | USP / FCC |
| Assay (C₅H₁₁NO₂) | ≥ 98.0 % and ≤ 102.0 % (on dry basis) | HPLC / Titration |
| Loss on Drying (105 °C) | ≤ 1.0 % | USP |
| Residue on Ignition (Sulphated Ash) | ≤ 0.1 % | USP |
| pH (10 % solution) | 5.0 – 7.0 | 25 °C |
| Heavy Metals (as Pb) | ≤ 10 ppm | USP <231> |
| Lead (Pb) | ≤ 2 ppm | ICP |
| Arsenic (As) | ≤ 1 ppm | ICP |
| Cadmium (Cd) | ≤ 1 ppm | ICP |
| Mercury (Hg) | ≤ 1 ppm | ICP |
| Chloride (Cl⁻) | ≤ 0.1 % | USP |
| Sulfate (SO₄²⁻) | ≤ 0.1 % | USP |
| Solubility | Freely soluble in water, clear solution | FCC |
| Microbiological Quality | Total Plate Count ≤ 10³ cfu/g; Yeast & Mold ≤ 10² cfu/g; E. coli, Salmonella negative | ISO / USP |
3. Specifications – Feed / Technical Grade
| Item | Specification / Typical Value |
|---|
| Appearance | White to off-white crystalline powder |
| Assay (C₅H₁₁NO₂) | ≥ 96.0 % |
| Moisture | ≤ 2.0 % |
| Residue on Ignition | ≤ 0.2 % |
| Heavy Metals (as Pb) | ≤ 20 ppm |
Typical Applications:
Poultry and swine feed additive (osmolyte, improves growth and carcass quality)
Aquaculture feed for stress reduction and improved feed conversion
4. Typical Applications
Nutraceuticals: Supports methylation, liver health, homocysteine metabolism
Sports Nutrition: Included in pre-workouts and endurance products
Food & Beverage: Fortified foods, functional nutrition
Feed Industry: Performance enhancer and anti-stress agent for livestock and aquaculture
5. Physical & Chemical Properties
Appearance: White crystalline powder
Taste: Mildly sweet
Solubility: Freely soluble in water, clear solution
Stability: Hygroscopic; store under dry conditions
6. Storage & Handling
Store in a cool, dry, well-ventilated area
Keep container tightly closed to avoid moisture uptake
Avoid prolonged exposure to air, light, and heat
Follow GMP / HACCP for food and pharma use
7. Packaging
Food / Pharma Grade: 25 kg fiber drum or paper bags with PE liner
Feed / Technical Grade: 25 kg woven bags, jumbo bags available
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