| Name | Bikinin |
| Description | Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor. |
| In vitro | Bikinin directly inhibited BIN2 in Arabidopsis GSK-3s and activated oleuropein steroid-dependent gene expression.Bikinin also inhibited RD26 expression and, in the case of RD26pro:GUS, NaCl (150 mM)-induced GUS activity. |
| In vivo | Bikinin directly inhibited BIN2 in Arabidopsis GSK-3s and activated oleuropein steroid-dependent gene expression.Bikinin also inhibited RD26 expression and, in the case of RD26pro:GUS, NaCl (150 mM)-induced GUS activity. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (7.32 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 100 mg/mL (366.19 mM), Sonication is recommended.
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| Keywords | Shaggy-like kinase | Inhibitor | inhibit | GSK-3 | GSK3 | Glycogen synthase kinase-3 | Glycogen synthase kinase 3 | Bikinin |
| Inhibitors Related | Cromolyn sodium | 4-Methyl-6-Methoxycoumarin | Indazole | GSK 3 Inhibitor IX | AT7519 | 5-Bromoindole | 4-Chloro-2'-bromoacetophenone | Ethyl linoleate | Ginsenoside Rg2 | GSK-3 Inhibitor 5 | (E/Z)-10-Hydroxy-2-decenoic acid | ROCK-IN-5 |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Kinase Inhibitor Library | Natural Product Library | Inhibitor Library | Neuroprotective Compound Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library |