1. Cardarine (GW-501516) is drug that binds to the PPAR receptor. It was discovered that Cardarine, when binding to the PPAR receptor, recruits what is called the coactivator PGC-1α enzyme, which then increases the expression of genes involved in the expenditure of energy. Rats treated with Cardarine were shown to have increased fatty acid metabolism and increased protection against obesity from eating a bad diet, as well as an increased protection from type-2 diabetes.
2. In another study on Rhesus monkeys, cardarine was shown to increase HDL (good cholesterol) and decrease LDL (bad cholesterol). Reasons for this effect appeared to be caused by an increased expression of the cholesterol transporter ABCA1. In other words, cardarine activates the same genetic pathways that are involved in exercise. In addition, cardarine was studied for use in treating cardio disease.
What is GW-501516
GW 501516 is the "ultimate endurance enhancer" - It's used by elite athletes and competitors for a reason.
Gives you insane energy levels - so you can push harder in the gym, increase your intensity, and bust through plateaus like never before.
Decreases recovery time - meaning you can lift almost every day while taking GW.Will rapidly melt fat, but is NON CATABOLIC. That means you'll keep all your gains while getting leaner.Will get you immediate, noticeable results: literally on the first dose.
Provides one of the cleanest energies. It's not a stimulant, so you won't crash or feel anxious at all.
The ability to run for as long as 12 weeks. You'll get better and better results the longer you take it.
Is versatile - can be stacked with virtually anything.
Can be used while cutting or bulking. Cardarine will accelerate your results no matter what you do.
Gives you an overall sense of health and well being. You'll feel amazing while you're on it.
No side effects, liver toxicity, or suppression have been reported. There's no need for PCT either.
Called the possible cure for obesity, Cardarine allows you to lose weight by using fat stores for energy rather than carbohydrates.
2. The Advantage of GW-501516 (Cardarine).
1. GW 501516 is the “ultimate endurance enhancer” - It’s used by elite athletes and competitors for a reason.
2. Gives you insane energy levels - so you can push harder in the gym, increase your intensity, and bust through plateaus like never before.
3. Provides one of the cleanest energies. It’s not a stimulant, so you won’t crash or feel anxious at all.
4. The ability to run for as long as 12 weeks. You’ll get better and better results the longer you take it.
5. Decreases recovery time - meaning you can lift almost every day while taking GW.
6. Will rapidly melt fat, but is NON CATABOLIC. That means you’ll keep all your gains while getting leaner.
7. Gives you an overall sense of health and well being. You’ll feel amazing while you’re on it.
8. No side effects, liver toxicity, or suppression have been reported. There’s no need for PCT either.
9. Will get you immediate, noticeable results: literally on the first dose.
10. Is versatile - can be stacked with virtually anything.
11. Can be used while cutting or bulking. Cardarine will accelerate your results no matter what you do.
12. Called the possible cure for obesity, Cardarine allows you to lose weight by using fat stores for energy rather than carbohydrates.
3. Cardarine: The Cure for Obesity
THE PRIMARY ROLE is GW’s ability to rid the body of unwanted fatty tissue and it has become almost LEGENDARY. The chemical compounds in this particular PPAR agonist functions in differentiation of adipocytes. Much like growth hormone, GW 501516 generates proinflammatory markers in adipose tissue and decreasing the activity of genes involved in lipogenesis. This means that the body is able to block fatty acid chains from forming and being stored as fat.
4. Recommendations & Dosing Guidelines for Cardarine
10-20 mg per day is a sufficient dose. It is recommended to start at 10mg per day to take advantage of the host’s sensitivity to the new chemical. 10 mg a day is aimed for endurance, and the higher the dosage the greater the fat loss benefits are going to be
Lab mice should be given dosages 45 minutes- 1 hour before exercise.
GW501516 has been tested for a 2 year study and has found no decreases or stagnation in effects. Most individuals run cycles for 12-14 weeks at a time with a 4-6 week break. This is normally to coincide with a SARM cycle, but there is no evidence showing that GW 501516 needs to be off-cycled after such a short amount of time. GW501516 was created for LONG TERM usage, so there is no reason why it shouldn’t be used that way.
Half life is between 16-24 hours and should be take at 10mg once a day or 10mg once every 10-12 hours if taken at a higher dose.
No PCT is needed, GW is recommended in combination with PCT if highly toxic anabolics have been used.
Highly recommended to use with a ketogenic diet.
Can be used in conjunction with anabolics and stimulants of any kind without adverse reactions.
5. How GW 501516 Works
GW 501516 stimulates glucose uptake and skeletal muscle tissue. It burns fat by stimulating fatty acid oxidation. It’s suggested as a potential treatment for obesity because of it’s ability to rapidly melt fat. Also, Cardarine is said to increase HDL by an average of 79% (good cholesterol) and decrease LDL (bad cholesterol) in current Phase II trials. GW 501516 is a PPARδ agonist. These help increase your HDL levels from an enhanced expression of the cholesterol transporter ABCA1.
6. The Side Effects of GW 501516
Not to say that there are none, but in the last 20 years no side effects have been seen by anyone studying the drug.
GW501516 has not only been tested in healthy subjects, but also those with simulated “real life” habits (such as drinking alcohol, stimulant narcotics, and the use of tobacco products). It is uncertain if there are long term ramifications, but no research has been published stating otherwise.
This is what makes Cardarine so incredibly popular and usable over long periods of time. In certain studies, there have even been signs showing the reversal of diabetes, obesity, Dyslipidemia and many other diseases.
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