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ChemicalBook Product Catalog API Antineoplastic agents Antimetabolites, Antineoplastic Carmofur

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Carmofur NEW

$34.00 50mg

$48.00 100mg

Min. Order
Purity99.98%
Cas No61422-45-5
Supply Ability10g
Update time2026-03-13

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP4Y

United States

United States

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Chemical Properties

Product Name	Carmofur
CAS No	61422-45-5
EC-No
Min. Order
Purity	99.98%
Supply Ability	10g
Release date	2026/03/13

Product Introduction

Bioactivity

Name	Carmofur
Description	Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
In vitro	Carmofur is one of the masked compounds of 5-FU, which was modified for more potent antineoplastic activity and less toxicity. Carmofur is converted in vivo into 5-FU directly or via intermetabolites, such as 1-(carboxypentylcarbamoyl)-5-fluorouracil and/or 1-(carboxypropylcarbomoyl)-5-fluorouraci. Carmofur and its metabolites gradually accumulate in the brain during continuous administration and are removed very slowly. Carmofur has potent neurotoxicity which can produce severe leucoencephalopathy resembling methotrexate leucoencephalopathy both clinically and on brain CT, together with a cerebellar syndrome similar to that following 5-FU neurotoxicity. [1]
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 250 mg/mL (971.78 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) Ethanol : 10 mg/mL (38.87 mM), Sonication is recommended.
Keywords	VirusProtease \| Virus Protease \| SARS-CoV \| SARSCoV \| SARS coronavirus \| RNASynthesis \| RNA Synthesis \| protease \| NucleosideAntimetabolite \| Nucleoside Antimetabolite/Analog \| Nucleoside Antimetabolite \| Mpro \| Inhibitor \| inhibit \| DNASynthesis \| DNA/RNA Synthesis \| DNA Synthesis \| derivative \| Carmofur \| antineoplastic \| Analog \| 5-fluorouracil
Inhibitors Related	Stavudine \| 5-Fluorouracil \| Phenytoin sodium \| Uridine \| Guanidine hydrochloride \| Hydroxychloroquine \| Hexane-1,6-diol \| 1,4-Naphthoquinone \| Adenine \| Carbazole \| Thymidine \| Usnic Acid
Related Compound Libraries	DNA Damage & Repair Compound Library \| Bioactive Compound Library \| Drug Repurposing Compound Library \| Anti-Viral Compound Library \| Inhibitor Library \| Anti-Cancer Approved Drug Library \| Lipid Metabolism Compound Library \| Anti-Aging Compound Library \| Bioactive Compounds Library Max \| Anti-Infection Compound Library \| Anti-Cancer Active Compound Library \| Anti-Cancer Drug Library

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