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Cefditoren pivoxil NEW

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Min. Order
Purity99.42%
Cas No117467-28-4
Supply Ability10g
Update time2026-04-10

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

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United States

United States

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Chemical Properties

Product Name	Cefditoren pivoxil
CAS No	117467-28-4
EC-No
Min. Order
Purity	99.42%
Supply Ability	10g
Release date	2026/04/10

Product Introduction

Bioactivity

Name	Cefditoren pivoxil
Description	Cefditoren pivoxil (ME 1207) is a semi-synthetic, broad-spectrum, beta-lactamase resistant, third-generation cephalosporin antibiotic with bactericidal activity.
In vitro	Cefditoren has MIC50/MIC90 results for Moraxella catarrhalis and Haemophilus influenzae of 0.12/0.5 and < or = 0.008/0.015 mg/mL, respectively. [1] Cefditoren (MIC(90), 0.5 mg/mL) is 4- to 128-fold more active than comparison beta-lactams against the pneumoococci and was the most potent beta-lactam (including penicillin) versus beta-haemolytic streptococci. Cefditoren (MIC(90) in mg/mL/% susceptible) activity against all tested H. influenzae (0.03/100) and M. catarrhalis (0.06-0.5/100) is comparable to Cefixime and significantly greater than cefaclor. Cefditoren pharmacokinetics demonstrate a T(1/2) of 1.5-2 hours and C(max) values of 2.8 and 4.6 mg/mL, respectively with 200 or 400 mg doses of Cefditoren pivoxil. [2] Cefditoren possesses a broad-spectrum of cidal antibacterial activity against both Gram-positive and Gram-negative species with stability to many beta-lactamases of clinical importance. [3] Cefditoren is also effective against methicillin-susceptible strains of Staphylococcus aureus. Cefditoren has compared favorably against other orally administered antibiotics used against the most commonly isolated respiratory tract pathogens. [4] Cefditoren up-regulates the expression levels of Mrp2, Bcrp and Oat2, and down-regulate P-gp and Oct1 mRNA expression. [5]
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (3.22 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 45 mg/mL (72.5 mM), Sonication is recommended.
Keywords	PBPs \| ME-1207 \| ME1207 \| Cefditoren pivoxil \| Bacterial \| Antibiotic
Inhibitors Related	Neomycin sulfate \| Adipic dihydrazide \| Levulinic acid \| Kanamycin sulfate \| D(+)-Raffinose pentahydrate \| Sulfamethoxazole sodium \| Terbinafine hydrochloride \| Metronidazole \| Doxycycline \| Dimethyl sulfoxide \| Sodium diacetate \| BES
Related Compound Libraries	Bioactive Compound Library \| Approved Drug Library \| Pediatric Drug Library \| Antibiotics Library \| Drug Repurposing Compound Library \| NO PAINS Compound Library \| FDA-Approved Drug Library \| Immunology/Inflammation Compound Library \| Bioactive Compounds Library Max \| Anti-Infection Compound Library \| NMPA-Approved Drug Library \| Human Metabolite Library

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