Basic information Safety Related Supplier

ChemicalBook Product Catalog Biochemical Engineering Biochemical Reagents Agonist Inhibitors CEP-28122

1/1

CEP-28122 NEW

$50.00 1mg

$135.00 5mg

$219.00 10mg

Min. Order
Purity99.87%
Cas No1022958-60-6
Supply Ability10g
Update time2026-04-17

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP2Y

United States

United States

show more

Enterprise Verified

Business Bank account Basic Contact Infomation Business Address Trade Company

Chemical Properties

Product Name	CEP-28122
CAS No	1022958-60-6
EC-No
Min. Order
Purity	99.87%
Supply Ability	10g
Release date	2026/04/17

Product Introduction

Bioactivity

Name	CEP-28122
Description	CEP-28122 is a highly potent and selective, orally active ALK inhibitor.
Kinase Assay	Flashplate assay for identification and evaluation of Aurora inhibitors: On this assay 384-well Basic Flashplate? as solid assay platform is used. The plates are coated overnight at 4 °C with dithiothreitol (DTT) at 100 μg/mL in PBS buffer and used after being washed twice with PBS. 5 μL of CCT137690 in 2% DMSO is added to each well followed by 15 μL master mix of kinase buffer (50 mM Tris pH 7.5, 10 mM NaCl, 2.5 mM MgCl2, 1 mM myelin basic protein (MBP), 20 μM ATP, and 0.025 μCi/μL 33P-ATP). Finally, 250 ng per well of Aurora-A enzyme is added. The plate is shaken for approximately 2 min on a flat-bed plate shaker and incubated for 2 hours at room temperature. The reaction is stopped by washing the plate twice on a 16-pin wash with 10 mM sodium pyrophosphate. The plate is then read on a TopCount-NXTTM. For the determination of the inhibitory activity against Aurora-B or Aurora-C, the same conditions are followed in the assay using Aurora-B or Aurora-C enzymes.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 10 mM, Sonication is recommended.
Keywords	Inhibitor \| inhibit \| Cluster of differentiation 246 \| CEP-28122 \| CEP28122 \| CEP 28122 \| CD246 \| Anaplastic lymphoma kinase (ALK) \| Anaplastic lymphoma kinase \| ALK tyrosine kinase receptor \| ALK
Inhibitors Related	Alectinib \| ALKBH5-IN-5 \| Alectinib hydrochloride \| Lorlatinib \| SB-431542 \| DMH-1 \| RepSox \| ALK-IN-1 \| EML4-ALK kinase inhibitor 1 \| Crizotinib \| Brigatinib \| A 83-01
Related Compound Libraries	Anti-Lung Cancer Compound Library \| Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| Kinase Inhibitor Library \| Tyrosine Kinase Inhibitor Library \| Post-Translational Modification Compound Library \| Bioactive Compounds Library Max \| Anti-Cancer Compound Library \| Anti-Cancer Active Compound Library

show more

Company Profile Introduction

You may like

Recommended supplier

Send Inquriy