| Name | Choline chloride |
| Description | Choline chloride (Biocoline) is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism. |
| In vitro | After oral administration of Choline chloride, clinical symptoms include restlessness, accelerated respiration, reduced activity, convulsions, wrinkled fur, unsteady gait, and respiratory distress. Choline chloride exhibits low acute oral toxicity. Some animals exhibit diarrhea following ingestion of Choline chloride. In one study, the autopsy revealed pulmonary inflammation in 30% of the rats in the high-dose group. |
| In vivo | In cell culture, a deficiency of choline can lead to apoptosis, also known as programmed cell death. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 27 mg/mL (193.37 mM), Sonication is recommended.
H2O : 26 mg/mL (186.21 mM), Sonication is recommended.
DMSO : 250 mg/mL (1790.45 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (23.63 mM), Sonication is recommended.
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| Keywords | Nicotinic acetylcholine receptors | nAChR | mAChR | Inhibitor | inhibit | Endogenous Metabolite | Choline chloride | Choline | anti-inflammatory | analgesic | alpha7 nicotinic receptor |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Formamide | Glycerol | Thymidine | Corn starch | Hyaluronic acid sodium (MW 20 kDa) | N,N-Dicyclohexylcarbodiimide | Gluconate Calcium |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Traditional Chinese Medicine Monomer Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Miao medicine Compound Library | Immunology/Inflammation Compound Library | Cosmetic Ingredient Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Food as Medicine Compound Library |
United States
