| Name | CK-869 |
| Description | CK-869, an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor with an IC50 of 7 μM, is a valuable tool for investigating the Arp2/3 complex. |
| Cell Research | Cells were treated in suspension with different concentrations of the compounds, allowed to adhere to the surface of a tissue culture dish for one hour, washed and the number of adherent cells counted and presented as a fraction of untreated cells (10X lens, 10 fields/condition).?For cell spreading assays, cells were treated with CK-869 in suspension, plated on coverslips coated with 5 μg/ml fibronectin for imaging[1]. |
| In vitro | CK-869 inhibits comet tail formation by L. monocytogenes with an IC50 value of 7 μM.It also impairs cell adhesion and cell spreading in MCF10A human breast epithelial cells[1]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 75 mg/mL (190.22 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.07 mM), Sonication is recommended.
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| Keywords | MicrotubuleAssociated | Microtubule Associated | Inhibitor | inhibit | CK-869 | CK869 | CK 869 | Arp2/3 Complex | Actin-related protein 2/3 complex |
| Inhibitors Related | Flubendazole | N-Phenylbenzylamine | Mebendazole | 4-Isopropoxybenzoic acid | Pregnenolone acetate | Oxfendazole | α-Cyclodextrin | Methylene Blue trihydrate | 2-Methylthiophenothiazine | Paclitaxel | 4'-Demethylepipodophyllotoxin | Albendazole |
| Related Compound Libraries | Bioactive Compound Library | Microtubule-Targeted Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | High-Efficiency Gene Editing Small Molecule Library |