| Name | CORM-3 |
| Description | CORM-3 is a carbon monoxide-releasing molecule with anti-inflammatory and cardioprotective activity. |
| In vitro | CORM-3 protects against hypoxia-reoxygenation and oxidative stress by promoting CO release in cardiac cells. [1] CORM-3 attenuates the inflammatory response induced by LPS in RAW264.7 murine macrophages. [2] CORM-3 also uncouples mitochondrial respiration via interaction with the phosphate carrier. [4] |
| In vivo | CORM-3 (40 mg/kg i.p.) prolongs the survival of murine cardiac grafts and attenuates organ rejection in CBA mice transplanted with BALB/c hearts. [1] CORM-3 (20 mg/kg i.p.) decreases cellular infiltration, joint inflammation and destruction in a collagen-induced arthritis mouse model. [3] |
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (169.72 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (11.2 mM), Sonication is recommended.
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| Keywords | Nuclear factor-κB | Nuclear factor-kappaB | NODlikeReceptor(NLR) | NODlikeReceptor | NOD-like Receptor (NLR) | NODlike Receptor (NLR) | NOD-like Receptor | NLR | NF-κB | NFκB | NF-kB | NFkB | Inhibitor | inhibit | CORM-3 | CORM 3 |
| Inhibitors Related | Stavudine | Sodium propionate | Ethyl palmitate | Kojic acid | Uridine | Fumaric acid | 1,4-Naphthoquinone | Glucosamine | Ethyl linoleate | N,N-Dimethylacetamide | Aluminum Hydroxide | Magnesium sulfate |
| Related Compound Libraries | Bioactive Compound Library | Antidepressant Compound Library | Anti-Breast Cancer Compound Library | Hematonosis Compound Library | Pyroptosis Compound Library | Anti-Prostate Cancer Compound Library | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Infection Compound Library | Transcription Factor-Targeted Compound Library |
United States
