| Name | cyclo(L-Pro-L-Tyr) |
| Description | Maculosin is a secondary metabolite of fungi and bacteria. |
| In vitro | Maculosin?acts as a host-specific phytotoxin, inducing formation of weeping necrotic lesions in leaves of spotted knapweed (C. maculosa) when used at a concentration of 10 μM.?Maculosin reduces the growth of the plant pathogenic bacteria X. axonopodis and R. solanacearum (MICs = 31.25 μg/ml) as well as the pathogenic oomycetes P. cactorum, P. capsici, P. cinnamomi, P. infestans, and P. ultimum when used at concentrations ranging from 10 to 100 mg/ml.?Maculosin also inhibits the growth of M. luteus, M. smegmatis, S. cerevisiae, C. albicans, C. neoformans, and A. niger when used in combination with pyrrolnitrin or banegasin. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (480.23 mM), Sonication is recommended.
10% DMSO+90% Saline : 3.3 mg/mL (12.68 mM), Sonication is recommended.
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| Keywords | spotted knapweed | non-toxicity | liver cancer | Inhibitor | inhibit | Cyclo(Tyr-Pro) | cyclo(L-Pro-L-Tyr) | cyclo(LProLTyr) | cyclo(L Pro L Tyr) | antioxidant | anti-cancer | Alternaria alternata | 967564 |
| Inhibitors Related | Sucrose | Neomycin sulfate | Calcium Propionate | Aceglutamide | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Glycerol | Thymidine | Gluconate Calcium | Dimethyl sulfoxide | Sodium bicarbonate |
| Related Compound Libraries | Cyclic Peptide Library | Bioactive Compound Library | Alkaloid Natural Product Library | Peptide Compound Library | Natural Product Library | Microbial Natural Product Library | NO PAINS Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Bitter Compound library | Bioactive Compounds Library Max | Human Metabolite Library |
United States
