Product Code: D014111
English Name: Dapagliflozin Impurity 111
English Alias: (2S,3S,4S,5R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-5-((R)-1,2-diacetoxyethyl)tetrahydrofuran-3,4-diyl diacetate
CAS No.：1469910-84-6
Molecular Formula: C₂₉H₃₃ClO₁₀
Molecular Weight: 577.02
As a key impurity of Dapagliflozin, it features a clear structure and controllable purity, which is suitable for qualitative and quantitative analysis of impurities in drug research and development to ensure the quality and safety of the main drug.
Applicable to the development of drug analysis methods, stability studies, and quality control, providing standardized impurity reference substances for pharmaceutical companies and research institutions.
Drug Research and Development: Used for impurity profile analysis of Dapagliflozin active pharmaceutical ingredients (APIs) and formulations, evaluating the formation pathway of impurities in the production process, and optimizing the synthesis process.
Quality Control: As a reference substance for analytical methods such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS), to detect the impurity content in drugs, in compliance with international pharmaceutical regulatory standards such as ICH.
Scientific Research: Supports preclinical studies on Dapagliflozin, exploring the impact of impurities on drug safety and efficacy.
Dapagliflozin, an SGLT2 inhibitor, is used for the treatment of type 2 diabetes. In the process of drug research, development, and manufacturing, impurity control is a key link to ensure drug quality. Dapagliflozin Impurity 111, as an impurity potentially generated during specific processes or degradation, needs to be monitored through strict analytical methods to ensure that the drug meets safety and efficacy requirements. The research on impurities typically involves the derivation of synthesis pathways, structural confirmation, and toxicological evaluation, which are important components of new drug applications and generic drug consistency evaluations.
Current research on Dapagliflozin impurities mainly focuses on impurity synthesis methods, analytical detection technologies, and toxicological evaluation. Studies on Dapagliflozin Impurity 111 have been carried out in pharmaceutical development enterprises and research institutions, including reducing its generation through optimized synthesis processes and establishing highly sensitive analytical methods for quantitative detection. With the development of the generic drug market and the improvement of international regulatory standards, the demand for this impurity reference substance and in-depth research (such as stability and metabolic pathways) will continue to increase to meet the requirements of drug registration and production quality control.
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E-mail: anna@molcoo.com
NOTE！
We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!
WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com
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