| Name | Dibenamine hydrochloride |
| Description | Dibenamine hydrochloride is a competitive and irreversible blocker of the β-adrenergic receptor. |
| In vitro | The irreversible inhibitory effects of dibenamine on the noradrenaline-, K- and Ba-induced contractions of rat's isolated vas deferens, particularly in relation to Ca. |
| In vivo | Dibenamine hydrochloride causes a significant increase in the rate of destruction of L-epinephrine in the mouse. Pretreatment with Dibenamine hydrochloride apparently slowed the conversion of Ccl4 to CHCL3. Dibenamine hydrochloride (25 mg/kg; s.c.) decreased the CHCl3, levels at 2 and 6 hr by 30%-50%[3]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (421.97 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (13.5 mM), Sonication is recommended. H2O : 33.33 mg/mL (112.51 mM), Sonication is recommended.
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| Keywords | β-adrenergic receptor | Inhibitor | inhibit | hepatotoxicity | epinephrine | Dibenamine hydrochloride | Dibenamine | Beta Receptor | AdrenergicReceptor | Adrenergic Receptor | adrenergic | Acetylcholine |
| Inhibitors Related | Trifluoperazine dihydrochloride | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Isoprenaline hydrochloride | D-Mannitol | Mianserin hydrochloride | Trazodone hydrochloride | Atenolol | Doxepin hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compounds Library Max | Adrenergic Receptor-Targeted Compound Library | GPCR Compound Library | Anti-Cancer Compound Library |