Domperidone

Description: Domperidone is a commonly used gastric prokinetic and antiemetic drug. It is more familiar to everyone as domperidone. Its other aliases include propidone, imidone, chlorperidone, meperidone, ludolin, doperidone, doperidone, propidone, etc. It is a white to slightly yellow powder with a bitter taste. It is almost insoluble in water, slightly soluble in ethanol, easily soluble in lactic acid, and soluble in citric acid. This product is a strong peripheral dopamine receptor antagonist. Domperidone can block the pre- and post-synaptic DA1 and DA2 receptors, antagonize the inhibitory effect of dopamine on the postsynaptic cholinergic neurons of the intestinal myometrial plexus, and cause gastric contraction.