| Name | [DPro10] Dynorphin A (1-11)acetate,porcine |
| Description | [DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine is an n-alkylated derivative with analgesic activity. |
| In vitro | Porcine [DPro10] Dynorphin A (1-11) inhibits adenylyl cyclase activity in CHO cells expressing k-opioid receptors, with an IC50 value of 0.12 nM[1]. |
| In vivo | Administered intracerebroventricularly (ICV), [DPro10] Dynorphin A (1-11), porcine, exhibits analgesic effects involving thermal cutaneous (tail-flick) and chemical visceral (acetic acid-induced writhing) stimuli, with known differential activation of mu and kappa receptors[2]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | κ-opioid receptor | OpioidReceptor | Opioid Receptor | [DPro10] Dynorphin A acetate,porcine |
| Inhibitors Related | Docusate sodium | Bevenopran | Mirtazapine | Matrine | (-)-Menthol | Cuminaldehyde | Progesterone | Naltrexone hydrochloride | Cebranopadol | BTRX-335140 | Bisacodyl | Mianserin hydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Anti-Neurodegenerative Disease Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Peptide Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |