| Name | (E)-Naringenin chalcone |
| Description | Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid that improves adipocyte metabolic functions and exerts insulin-sensitizing effects by activating an adiponectin-related pathway. Naringenin chalcone exhibits anti-inflammatory properties by inhibiting the production of proinflammatory cytokines in the interaction between adipocytes and macrophages, may be useful for ameliorating the inflammatory changes in obese adipose tissue. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 49 mg/mL (179.98 mM), Sonication is recommended. Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc. : Soluble 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (7.35 mM), Sonication is recommended.
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| Keywords | skin | Naringenin chalcone | metabolites | Inhibitor | inhibit | Inflammatory | flavonoids | disorders | allergic | 2′,4,4′,6′-Tetrahydroxychalcone | 2′,4,4′,6′Tetrahydroxychalcone | 2′,4,4′,6′ Tetrahydroxychalcone |
| Inhibitors Related | Stavudine | Aceglutamide | Tamoxifen | Urea | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Gluconate Calcium | Dimethyl phthalate | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Polyphenolic Natural Product Library | Flavonoid Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library |