| Name | Eberconazole Nitrate |
| Description | Eberconazole Nitrate (Ebernet) is an azole antifungal agent and broad-spectrum imidazole derivative. |
| Animal Research | Eberconazole Nitrate(EB) microsponges were prepared using the quasiemulsion solvent diffusion method.?The effect of formulation variables (drug:polymer ratio, internal phase volume and amount of emulsifier) and process variables (stirring time and stirring speed) on the physical characteristics of microsponges were investigated.?The optimized microsponges were dispersed into a hydrogel and evaluated[1]. |
| In vivo | Spherical and porous Eberconazole Nitrate(EB) microsponge particles were obtained.?The optimized microsponges possessed particle size, drug content and entrapment efficiency of 24.5 μm, 43.31% and 91.44%, respectively.?Microsponge-loaded gels demonstrated controlled release, nonirritancy to rat skin and antifungal activity.?An in vivo skin deposition study demonstrated fourfold higher retention in the stratum corneum layer as compared with commercial cream[1]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.1 mM), Sonication is recommended.
DMSO : 25 mg/mL (63.74 mM), Sonication is recommended.
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| Keywords | topical administration | miconazole | ketoconazole | Inhibitor | inhibit | Fungal | Eberconazole Nitrate | Eberconazole | dichlorinated imidazole derivative | dermatophytose | clotrimazole | Antifungal |
| Inhibitors Related | Calcium Propionate | Dehydroacetic acid sodium | Potassium gluconate | D-Gluconic acid (solution) (50% in H2O) | Sulfacetamide sodium | Benzyl propionate | Terbinafine hydrochloride | Sodium formate | Magnesium acetate tetrahydrate | Geraniol | L-Citronellol | Benzimidazole |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Anti-Fungal Compound Library | Drug Repurposing Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
United States
