Synonym: Esomeprazole Sodium; Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide; (s)-omeprazole sodium salt
Molecular Formula: C34H36MgN6O6S2
Molecular Weight: 713.12 g/mol
Appearance: Solid powder
Purity: 99.00~101.00%
Boiling Point: 156 °C (approx)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Keep container tightly closed in a dry and well-ventilaed place.
Solubility: Soluble inacetone, alcohol and dioxane; Practically insoluble in water; Sparingly soluble invegetableoils.
Shelf Life: >2 years if stored properly
HS Tariff Code: 29333990.90
Description:
Esomeprazole sodium, the sodium salt form of esomeprazole, is a commonly used antiulcer drug and is a proton pump inhibitor. Proton pump inhibitors (PPIs) are the drugs of choice for the treatment of acid-related diseases such as peptic ulcer and gastroesophageal reflux disease. Currently there are five commonly used PPIs in clinical practice: omeprazole, lansoprazole, rabeprazole, pantoprazole and esomeprazole. Esomeprazole is the S-isomer of omeprazole, which reduces gastric acid secretion through a specific raking mechanism of action, and is a specific inhibitor of the proton pump in the mural cells. Due to the metabolic advantages, Esomeprazole sodium has higher bioavailability and more consistent pharmacokinetics than omeprazole, which leads to an increase in the drugs reaching the proton pump, and the control of gastric acid is significantly superior to that of other proton pumps such as Lansoprazole, Pantoprazole, and Rabeprazole. Lansoprazole, pantoprazole and rabeprazole.
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