| Name | Ethambutol dihydrochloride |
| Description | Ethambutol dihydrochloride is an anti-mycobacterial compound that inhibits arabinosyl transferase activity to prevent cell wall formation and can be used to induce hyperuricemia models. |
| In vitro | Ethambutol primarily targets the product of the embB gene, inducing mutations within the emb gene in drug-resistant strains of tuberculosis. In Mycobacterium smegmatis, Ethambutol affects arabinogalactan and lipoarabinomannan biosynthesis. |
| In vivo | In animal models, Ethambutol is administered orally at a dosage of 100 mg/kg. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 60 mg/mL (216.42 mM), Sonication is recommended. H2O : 51 mg/mL (183.96 mM), Sonication is recommended.
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| Keywords | Inhibitor | inhibit | Ethambutol Dihydrochloride | Ethambutol | Emb Dihydrochloride | Emb | CL-40881 | CL 40881 | Bacterial | Antifungal | Antibiotic |
| Inhibitors Related | Neomycin sulfate | Calcium Propionate | Adipic dihydrazide | Levulinic acid | D(+)-Raffinose pentahydrate | Benzyl propionate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | Sodium bicarbonate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Failed Clinical Trials Compound Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Anti-Fungal Compound Library | Natural Product Library | Drug Repurposing Compound Library | Microbial Natural Product Library | FDA-Approved Drug Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max |