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ChemicalBook Product Catalog FIDAS-3

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FIDAS-3 NEW

$44.00 5mg

$71.00 10mg

$136.00 25mg

Min. Order
Purity98.59%
Cas No1266684-01-8
Supply Ability10g
Update time2026-04-16

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP6Y

United States

United States

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Chemical Properties

Product Name	FIDAS-3
CAS No	1266684-01-8
EC-No
Min. Order
Purity	98.59%
Supply Ability	10g
Release date	2026/04/16

Product Introduction

Bioactivity

Name	FIDAS-3
Description	FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding.
In vitro	FIDAS-3 induces the expression of cell cycle inhibitor, p21WAF1/CIP1. FIDAS-3 (10 μM; 36 h) treatment reduces the levels of both S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) in LS174T cells.FIDAS-3 (3 μM; 7 days; LS174T cells) treatment significantly inhibits the proliferation of LS174T cells. FIDAS-3 (3-10 μM) treatment inhibits the expression of c-Myc and cyclinD1 in LS174T CRC cells.
In vivo	FIDAS-3 (20 mg/kg;intraperitoneal injection;daily;for one months;C57BL/6J athymic nude mice) treatment significantly inhibits the growth of xenograft tumors.
Storage	Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	10% DMSO+40% PEG300+5% Tween 80+45% Saline : 3.3 mg/mL (12.73 mM), Sonication is recommended. DMSO : 90 mg/mL (347.1 mM), Sonication is recommended.
Keywords	β-catenin \| βcatenin \| Wnt/β-catenin \| Wnt/betacatenin \| Wnt/b-catenin \| Wnt \| SAM \| SAH \| S-adenosylmethionine \| MethionineAdenosyltransferase(MAT) \| MethionineAdenosyltransferase \| Methionine S-adenosyltransferase 2A(MAT2A) \| Methionine Adenosyltransferase (MAT) \| Methionine Adenosyltransferase \| MATA2 \| MAT2A \| MAT \| Inhibitor \| inhibit \| FIDAS-3 \| FIDAS3 \| FIDAS 3 \| CyclinD1 \| c-Myc \| beta-catenin \| betacatenin \| bcatenin \| anti-proliferation \| anti-cancer
Inhibitors Related	Chlorquinaldol \| Urea \| Wnt pathway activator 1 \| Neohesperidin \| XAV-939 \| Ethyl linoleate \| Monensin sodium salt \| Nimbolide \| Isoquercetin \| (±)-Nornicotine \| Methyl Vanillate \| Bisdemethoxycurcumin
Related Compound Libraries	Reprogramming Compound Library \| Anti-Pancreatic Cancer Compound Library \| Bioactive Compound Library \| Anti-Alzheimer's Disease Compound Library \| Epigenetics Compound Library \| Anti-Cancer Metabolism Compound Library \| Neuroprotective Compound Library \| Inhibitor Library \| Anti-Prostate Cancer Compound Library \| Bioactive Compounds Library Max \| Anti-Cancer Compound Library \| Anti-Cancer Active Compound Library

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