| Name | Gomisin D |
| Description | Gomisin D is a natural product.Gomisin D is used as a quality marker of Shengmai San and shenqi Jiangtang Granule.Gomisin D is a potential antidiabetic and anti-Alzheimer's agent. |
| In vitro | Using exhaustive chromatographic separation we have isolated (-)-tigloyl-deangeloyl-gomisin F as a novel dibenzocyclooctadiene lignan from schisandra chinensis. With the help of HPLC, we further isolated (+)-schisandrin, (+)-deoxyschisandrin, (+)-γ-schisandrin, (-)-gomisin J, (+)-gomisin A, (-)-gomisin N, (-)-tigloyl-gomisin P, (-)-wuweizisu C, (-)-Gomisin D, rubrisandrin A, (-)-gomisin G, (+)-gomisin K (3) and (-)-schisantherin C. A full NMR description of (-)-schisantherin C was carried out with the aim to confirm previous reports of its structure. Compounds isolated were identified on the basis of UV, IR, (1)H- and (13)C-NMR and MS. The cytotoxicity of lignans was tested for the BY-2 cell line alone and as a synergistic effect with the cytotoxic agent camptothecin. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 9 mg/mL (16.96 mM), Sonication is recommended.
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| Keywords | Inhibitor | inhibit | Gomisin D |
| Inhibitors Related | Jaceosidin | Niflumic acid | 1,2,3,6-Tetragalloylglucose | Deferiprone | Salicylamide | Mycophenolic acid | Demethylzeylasteral | Bakuchiol | Cremophor EL | Licochalcone A | Gitogenin | Corylifol A |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Anti-Diabetic Compound Library | Selected Plant-Sourced Compound Library | Chinese Pharmacopoeia Natural Product Library | Natural Product Library | NO PAINS Compound Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library |