| Name | Hexaconazole |
| Description | Hexaconazole ((-)-Hexaconazol) is a broad-spectrum triazole fungicide that inhibits ergosterol biosynthesis via inhibition of the cytochrome P450-dependent 14α-demethylation of lanosterol, which results in disruption of the fungal cell membrane and cell death. |
| Cell Research | The medium was poured into a set of two petriplates under aseptic conditions in a laminar flow hood.?When the medium in the plates was solidified, a mycelial disc of 0.5 cm diameter of freshly grown test fungi taken from periphery was inoculated upside down at the center of the plates.?These treated petri dishes were incubated at 28℃ until fungal growth in the control plates was almost complete.?Hexaconazole used as commercial fungicide and acetone served as control.?All the compounds were tested in triplicates.?The mycelia growth of fungi (mm) in both treated (T) and control (C) petri plates was measured diametrically in three different directions and growth inhibition (I) and corrected inhibition (IC) were calculated by using Abbott s formula[2] |
| In vitro | Hexaconazole is fungicidal against the powdery mildews B. graminis and S. cucurbitae on cucumber plants in a concentration-dependent manner and is curative against powdery mildew on barley plants when used at a concentration of 6.7 mg/L[1].It also inhibits growth of R. bataticola and S. rolfsii (ED50s = 6.35 and 1.27 mg/L, respectively)[2]. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (6.37 mM), Sonication is recommended.
DMSO : 55 mg/mL (175.04 mM), Sonication is recommended.
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| Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species | Inhibitor | inhibit | Hexaconazole | Hexaconazol | Fungal | Antifungal |
| Inhibitors Related | Calcium Propionate | Ethoxyquin | Kaolin | Allopurinol | Cysteamine hydrochloride | Benzyl propionate | Terbinafine hydrochloride | Sodium formate | Ethyl linoleate | Magnesium acetate tetrahydrate | Geraniol | Dimethyl phthalate |
| Related Compound Libraries | Pesticide Compound Library | NF-κB Signaling Compound Library | Bioactive Compound Library | Anti-Ovarian Cancer Compound Library | Anti-Fungal Compound Library | Antioxidant Compound Library | Inhibitor Library | Anti-Fibrosis Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library |
United States
