| Name | Homovanillyl alcohol |
| Description | Homovanillyl alcohol, a biological metabolite of Hydroxytyrosol, is a phenolic compound found in virgin olive oil (VOO) and wine. It exhibits high scavenging activities, protects red blood cells from hemolysis in a dose-dependent manner, and has a protective effect on cardiovascular disease and total mortality. |
| In vitro | Structurally related compounds have been assayed for their ability to reduce homocysteine-induced monocyte adhesion as well as the cell surface expression of intercellular adhesion molecule-1 (ICAM-1) in EA.hy.926 cells. As well-known, among the selected phenolic compounds, hydroxytyrosol, Homovanillyl alcohol, and the hydroxycinnamic acid derivatives caffeic and ferulic acid display high scavenging activities, while tyrosol and p-coumaric acid are poorly active. All of the tested compounds, approaching potential in vivo concentrations, significantly reduce homocysteine-induced cell adhesion and ICAM-1 expression. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (743.21 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (11.89 mM), Sonication is recommended.
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| Keywords | TNF-α | Inhibitor | inhibit | Homovanillyl alcohol | DrugMetabolite | Drug Metabolite |
| Inhibitors Related | Kaolin | Undecane | 2-(Methylamino)benzoic acid | Acetylcysteine | Ethyl palmitate | Gum arabic | 1,8-Cineole | Dodecane | 1,4-Naphthoquinone | Tributyrin | Glucosamine | 10-Undecen-1-ol |
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