PRODUCT INFORMATION
| Common Name | Hydroxy-PEG4-acid |
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| CAS Number | 937188-59-5 | Molecular Weight | 266.288 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 420.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C11H22O7 | Melting Point | N/A |
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| MSDS | N/A | Flash Point | 155.5±20.8 °C |
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Use of Hydroxy-PEG4-acid
Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
Names
| Name | 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid |
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| Synonym | More Synonyms |
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Hydroxy-PEG4-acid Biological Activity
| Description | Hydroxy-PEG4-acid is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. |
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| References | [1]. Tinya Abrams, et al. Antibody drug conjugates. WO2016203432A1. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 420.7±40.0 °C at 760 mmHg |
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| Molecular Formula | C11H22O7 |
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| Molecular Weight | 266.288 |
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| Flash Point | 155.5±20.8 °C |
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| Exact Mass | 266.136566 |
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| LogP | -2.07 |
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| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
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| Index of Refraction | 1.466 |
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Synonyms
| MFCD22574805 |
| 1-Hydroxy-3,6,9,12-tetraoxapentadecan-15-oic acid |
| 3,6,9,12-Tetraoxapentadecan-15-oic acid, 1-hydroxy- |
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