| Name | Iberin |
| Description | Iberin (NSC-321801) induces apoptosis and inhibits cell survival (IC50 = 2.3 μM). Iberin is an analog of sulforaphane. |
| In vitro | Iberin inhibits neuroblastoma cell growth in a dose- and time-dependent manner and inhibits the expression of cyclin-dependent kinase Cdk2, Cdk4, and Cdk6 proteins. Iberin increases the apoptotic cell death and activates caspase-9, caspase-3, and PARP[2]. |
| In vivo | Iberin enhances tissue levels of the phase II detoxification enzymes quinone reductase and GST in a variety of rat tissues[5]. |
| Storage | keep away from moisture,store under nitrogen,store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 9 mg/mL (55.13 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (30.63 mM), Sonication is recommended. DMSO : 279 mg/mL (1708.93 mM), Sonication is recommended.
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| Keywords | NSC-321801 | NSC321801 | Iberin | Human Endogenous Metabolite | EndogenousMetabolite | Endogenous Metabolite |
| Inhibitors Related | Sucrose | Neomycin sulfate | Aceglutamide | Nicotinamide riboside malate | DL-Lysine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Glycerol | Thymidine | Gluconate Calcium | Dimethyl sulfoxide | Sodium bicarbonate |
| Related Compound Libraries | Apoptosis Compound Library | Food Sourced Compound Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Natural Product Library | Anti-Bacterial Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Bioactive Compounds Library Max | Human Metabolite Library |