Technical Data Sheet (TDS) – Icariin
Product Name: Icariin
Botanical Source: Epimedium spp.
CAS Number: 489-32-7
Synonyms: Epimedium Extract, Horny Goat Weed Extract
Grade: Food & Industrial
Storage: Store in a cool, dry place, away from light
1. Product Description
Icariin is a flavonoid glycoside extracted from the leaves of Epimedium species. It is a yellow to brownish-yellow fine powder with characteristic odor and bitter taste. It is widely used in nutraceuticals, functional foods, dietary supplements, and pharmaceutical intermediates.
2. Physical & Chemical Properties
| Property | Specification |
|---|
| Appearance | Yellow to brownish-yellow fine powder |
| Odor | Characteristic |
| Taste | Bitter |
| Solubility | Sparingly soluble in water, soluble in ethanol |
| Particle Size | 100% pass 80 mesh |
| Moisture (Loss on Drying) | ≤ 5% |
| Ash Total | ≤ 1% |
| pH (1% solution) | 5.0 – 7.0 |
| Storage Stability | Stable for 24 months under recommended conditions |
3. Identification
（1）HPLC: Retention time consistent with Icariin reference standard
（2）UV: Characteristic absorption peak
（3）IR: Functional group matching reference standard
4. Assay (Content of Icariin)
| Test Item | Specification | Result Example | Test Method |
|---|
| Icariin | ≥ 98% | 98.5% | HPLC |
5. Purity & Impurities
| Item | Specification | Result Example |
|---|
| Loss on Drying | ≤ 5% | 3.2% |
| Ash Total | ≤ 1% | 0.6% |
| Heavy Metals (Total) | ≤ 10 ppm | 5 ppm |
| Lead (Pb) | ≤ 2 ppm | 0.8 ppm |
| Arsenic (As) | ≤ 1 ppm | 0.2 ppm |
| Cadmium (Cd) | ≤ 1 ppm | 0.1 ppm |
| Mercury (Hg) | ≤ 0.1 ppm | <0.05 ppm |
| Residual Solvents | Comply with USP/EP limits | Complies |
6. Microbial Limits (Food Grade Only)
| Item | Specification | Result Example |
|---|
| Total Plate Count | ≤ 1000 CFU/g | 220 CFU/g |
| Yeast & Mold | ≤ 100 CFU/g | 18 CFU/g |
| E. coli & Salmonella | Negative | Negative |
7. Applications
Food & Nutraceuticals:
（1）Functional food and beverages
（2）Dietary supplements
（3）Herbal extracts and capsules
Industrial & Pharmaceutical:
（1）Intermediate for synthesis of pharmacological compounds
（2）Research and development of cardiovascular and hormonal products
（3）Cosmetics and topical formulations
8. Packaging
| Packaging Type | Net Weight |
|---|
| Paper drum with double-layer PE bag | 25 kg/drum |
| Customized packaging available | On request |
9. Safety & Handling
（1）Avoid inhalation of dust
（2）Avoid contact with eyes and skin
（3）Use in well-ventilated area
（4）Refer to SDS for detailed safety information
10. Shelf Life
（1）24 months when stored in original, unopened packaging under recommended conditions
Conclusion: This Icariin batch meets the specifications for both food-grade and industrial-grade applications.
China
