| Name | Imiquimod |
| Description | Imiquimod (R 837) is an immune response modifier and a toll-like receptor 7 (TLR7) agonist with antiviral and antitumor effects. It is used in the study of external genital warts, perianal warts, cancer, and COVID-19, and is commonly employed to induce psoriasis models. |
| In vivo | In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1]. |
| Storage | keep away from direct sunlight,store at low temperature,store under nitrogen | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : Insoluble
DMSO : 1 mg/mL (4.16 mM), Sonication and heating are recommended.
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| Keywords | warts | vulvar | Toll-like Receptor (TLR) | TLR8 | TLR7 | TLR | squamous | SARS-CoV | SARSCoV | SARS coronavirus | S26308 | S 26308 | R-837 | R837 | papillomavirus | nongenital | neoplasia | molluscum | keratosis | intraepithelial | Inhibitor | inhibit | infection | Imiquimod | human | HSV | Herpes simplex virus | disease | contagiosum | cell | carcinoma | Bowen's | basal ,cell | Autophagy | actinic |
| Inhibitors Related | Stavudine | Aceglutamide | Hemin | Tamoxifen | Cysteamine hydrochloride | Guanidine hydrochloride | Hydroxychloroquine | Enzalutamide | Paeonol | Naringin | Alginic acid | Sildenafil citrate |
| Related Compound Libraries | Bioactive Compound Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
United States
