Product Name: Iodobenzene-d5 (Perdeuterated Iodobenzene)
CAS No.: 1898-70-2
Molecular Formula: C₆D₅I
Molecular Weight: 209.03 g/mol
Overview:
Iodobenzene-d5 is a high-value, perdeuterated aromatic reagent and synthetic building block, in which all five hydrogen atoms on the benzene ring are replaced by the stable isotope deuterium (D). This perdeuteration completely eliminates proton signal interference in NMR spectroscopy, making it an ideal "silent" aromatic solvent and inert internal standard. Crucially, it retains the excellent reactivity of iodobenzene, serving as a key deuterated aryl precursor to efficiently introduce the phenyl-d₅ group into complex molecular frameworks via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Buchwald-Hartwig). This enables the synthesis of structurally defined deuterium-labeled molecules for drug metabolism studies, materials science, and mechanistic investigations.
Key Advantages:
Ultra-High Isotopic & Chemical Purity: We offer perdeuterated product with a deuterium enrichment of up to 99.9 atom % D and a consistent chemical purity of ≥98%, ensuring flawless performance in the most sensitive analyses and demanding synthetic applications.
Dual-Function Excellence: It functions both as a premium deuterated NMR solvent (especially interference-free in the aromatic region) and as a versatile, key building block for synthesizing high-value-added deuterated aryl compounds, offering high cost-effectiveness.
Stable Supply & Professional Quality: Utilizing advanced deuteration processes, we guarantee stable production and supply from gram to hundred-gram scale. The product is rigorously purified, featuring extremely low levels of moisture and impurities, with excellent batch-to-batch consistency.
Physicochemical Properties:
Appearance: Colorless to pale yellow clear liquid.
Density: ~1.83 g/mL (25°C).
Boiling Point: ~188 °C.
Melting Point: ~ -29 °C.
Refractive Index: n²⁰/D ~1.620.
Solubility: Soluble in most organic solvents, e.g., diethyl ether, ethanol, benzene.
Primary Applications:
NMR Spectroscopy: Serves as a premium deuterated solvent free of interference in the aromatic region for dissolving samples with signals in the aliphatic region or providing a lock signal in solvent mixtures, significantly improving spectral quality.
Mass Spectrometry & Metabolic Studies: Used as a deuterated internal standard or labeling precursor to synthesize deuterated drug analogs for precise quantification in analyses like LC-MS/MS and for studying drug metabolites and pathways.
Organic Synthesis & Materials Chemistry: Acts as a crucial deuterated aryl source to prepare deuterated benzene ring-containing liquid crystals, organic light-emitting materials (OLEDs), functional polymers, and pharmaceutical intermediates via coupling reactions, facilitating structure-property relationship studies.
Reaction Mechanism Studies: Leverages its perdeuterated nature and kinetic isotope effects to investigate detailed mechanisms of reactions involving aromatic rings.
Packaging & Storage:
Packaging: Available in various sealed glass vials (typically amber) with PTFE-lined caps in sizes such as 1Kg, 5Kg, 10Kg, 25Kg, 50Kg, 100Kg, etc. Custom packaging is available upon request.
Storage: This product is light-sensitive. It is recommended to store tightly sealed, protected from light, and refrigerated at 2-8°C. For long-term storage, inert gas purging is advisable. After opening, handle under dry, inert atmosphere.
We welcome inquiries, collaboration, and sample requests from research experts and industrial partners in advanced analytical testing, drug development, materials science, and synthetic methodology!
Yurui(Shanghai) Chemical Co. Ltd / UIV Chem
Contact Person: Nan Haodong
Address: Floor 5, Building H2, No.3188 Xiupu Rd, Pudong, Shanghai 201203, China
Tel: 0086-21-50456736 / 021-33191321
WhatsApp: +86 17613296318
WeChat: NHDong2021
Email: xin@riyngroup.com
QQ: 2551819264
Website: www.riyngroup.com
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