| Name | Isotrifoliin |
| Description | Isotrifoliin (Isoquercitroside)n is an effective antioxidant and an eosinophilic inflammation suppressor. |
| In vitro | Isoquercitrin occurs widely in plants.10 μM of Isoquercitrin of the seven compounds partially but significantly blunt the negative effect of H2O2 on RGC-5 cells, as the viability of cells in the presence of H2O2 is increased from approximately 63% to 83% and 90% at 10 and 50 μM, respectively. Indeed, 50 μM Isoquercitrin is more effective as a neuroprotectant than the same concentration of EGCG. |
| In vivo | In animal studies, both Isoquercitrin and quercetin administration resulted in reduced eosinophil counts in the bronchoalveolar lavage fluid (BALF), blood, and lung parenchyma. Isoquercitrin-treated mice uniquely exhibited decreased neutrophil counts in blood and lower IL-5 concentrations in lung homogenates. No significant changes were observed in mononuclear cell counts. |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 125 mg/mL (269.18 mM), Sonication is recommended.
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| Keywords | ReactiveOxygenSpecies | Reactive Oxygen Species | Isotrifoliin | ISOQUERCITRIN | Inhibitor | inhibit |
| Inhibitors Related | Ethoxyquin | Cysteamine hydrochloride | Acetylcysteine | L-Ascorbic acid | Dimethyl fumarate | Glucosamine | D-(+)-Glucono-1,5-lactone | L-Cystine | (-)-Epigallocatechin Gallate | L-Ascorbic acid sodium salt | Sodium 2-oxopropanoate | Arecoline |
| Related Compound Libraries | Polyphenolic Natural Product Library | Medicinal and aromatic plants natural product library | Inhibitor Library | Metabolism Compound Library | Cosmetic Ingredient Compound Library | Oxidation-Reduction Compound Library |
United States
