Lapatinib 4-Fluoro Impurity ;1026818-86-9
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com
Product Number: L079002
English Name: Lapatinib 4-Fluoro Impurity
English Alias: N-(3-chloro-4-((4-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
CAS Number: 1026818-86-9
Molecular Formula: C29H26ClFN4O4S
Molecular Weight: 581.06
Product Advantages: Lapatinib 4-Fluoro Impurity has high purity and good chemical stability. Its structure has been strictly confirmed by multiple precise analytical methods such as nuclear magnetic resonance and mass spectrometry, and it remains stable and uniform under different experimental conditions and storage environments. As a reference substance, it can be accurately used for the detection and analysis of Lapatinib impurities, ensuring accurate, reliable, and highly reproducible detection results, providing a solid guarantee for pharmaceutical quality research and quality control, and facilitating quality monitoring in drug research, development, and production processes.
Application Fields:
Quality Control: As an impurity reference standard, it is used to establish and validate the detection methods for impurities in Lapatinib bulk drugs and formulations, ensuring that the sensitivity and specificity of the detection methods meet pharmaceutical quality standard requirements and effectively guaranteeing drug quality.
Process Optimization: During the production of Lapatinib, by monitoring the content of this impurity and analyzing the stages and causes of its generation, it helps to optimize the synthesis process, reduce impurity formation, and improve product quality and production efficiency.
Stability Studies: In drug stability tests, it analyzes the changes of this impurity under different storage conditions (such as temperature, humidity, light), providing key data support for determining the shelf life and storage conditions of drugs, and ensuring the quality stability of drugs during storage and transportation.
Background Description: Lapatinib is an important targeted drug for the treatment of HER2-positive breast cancer. In its research, development, production, and quality control processes, impurity research is a crucial aspect to ensure drug safety and effectiveness. The presence of impurities may affect the drug's efficacy and even cause potential toxic and side effects. As a related impurity of Lapatinib, in-depth research on Lapatinib 4-Fluoro Impurity helps to comprehensively evaluate the quality of Lapatinib drugs, improve the drug quality evaluation system, and ensure the safety and effectiveness of clinical medication.
Research Status: Currently, research on Lapatinib 4-Fluoro Impurity continues to progress. In terms of detection technology, advanced detection methods such as Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) and high-resolution mass spectrometry are constantly being explored to achieve precise detection of trace impurities. In the study of impurity generation mechanisms, the formation causes and influencing factors are deeply analyzed by simulating drug synthesis reactions and storage environments, providing a theoretical basis for optimizing the production process and controlling impurities from the source. In addition, research on the impact of this impurity on the efficacy and safety of Lapatinib is also gradually being carried out, aiming to further clarify its role in drug quality evaluation and provide more comprehensive evidence for rational clinical medication.
NOTE！
We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com
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