Lapatinib Impurity 10;202197-26-0
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com
Product Number: L079010
English Name: Lapatinib Impurity 10
English Alias: 3-chloro-4-((3-fluorobenzyl)oxy)aniline
CAS Number: 202197-26-0
Molecular Formula: C₁₃H₁₁ClFNO
Molecular Weight: 251.68
Product Advantages: Lapatinib Impurity 10 has high purity and good stability. Its molecular structure is accurately determined through rigorous structural identification methods (such as nuclear magnetic resonance and mass spectrometry analysis). Under different experimental conditions and storage environments, its properties remain stable and uniform. It can be used as a reliable reference substance for the detection and analysis of Lapatinib impurities, ensuring the accuracy and repeatability of detection results, and providing strong support for pharmaceutical quality research and quality control.
Application Fields:
Quality Control: As an impurity reference standard, it is used to establish and validate the detection methods for impurities in Lapatinib bulk drugs and formulations, ensuring that the sensitivity and specificity of the detection methods meet the requirements of pharmaceutical quality standards and guaranteeing drug quality.
Process Optimization: During the production of Lapatinib, by monitoring the content of this impurity and tracing the process steps where it is generated, it helps to optimize the synthesis route, reduce impurity formation, and improve product quality and production efficiency.
Stability Studies: In drug stability tests, it analyzes the change trends of this impurity under different storage conditions (such as temperature, humidity, light), providing key data for determining the shelf life and storage conditions of drugs.
Background Description: Lapatinib is an important targeted drug for the treatment of HER2-positive breast cancer. In the process of its research, development, production, and quality control, impurity research is the key to ensuring drug safety and effectiveness. The presence of impurities may affect the pharmacological activity of the drug and even cause potential adverse reactions. As a related impurity of Lapatinib, in-depth research on Lapatinib Impurity 10 helps to comprehensively evaluate the quality of Lapatinib drugs and ensure the safety and effectiveness of clinical medication.
Research Status: Currently, research on Lapatinib Impurity 10 mainly focuses on detection technology and impurity generation mechanisms. In terms of detection technology, advanced methods such as Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) and high-resolution mass spectrometry are used to achieve precise detection of trace impurities. In the study of impurity generation mechanisms, the key steps and influencing factors of its formation are analyzed by simulating the drug synthesis reaction process, providing a theoretical basis for optimizing the production process and controlling impurities from the source. In addition, research on the impact of this impurity on the efficacy and safety of Lapatinib is also gradually being carried out
NOTE！
We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com
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