Lapatinib Impurity 8;845271-73-0
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com
Product Number: L079008
English Name: Lapatinib Impurity 8
English Alias: N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine
CAS Number: 845271-73-0
Molecular Formula: C₂₁H₁₅ClFN₃O
Molecular Weight: 379.81
Product Advantages: Lapatinib Impurity 8 has extremely high purity and good chemical stability. Its structure has been accurately confirmed by rigorous spectroscopic analysis (such as nuclear magnetic resonance and mass spectrometry), and it remains stable and uniform under different experimental environments and storage conditions. As a reference substance, it can be accurately used for Lapatinib impurity detection, ensuring the accuracy and repeatability of detection results, and providing a solid and reliable basis for pharmaceutical quality research and quality control.
Application Fields:
Quality Control: As an impurity reference standard, it is used to establish and validate the detection methods for impurities in Lapatinib bulk drugs and formulations, ensuring that the detection methods have high sensitivity and specificity and meet pharmaceutical quality standard requirements.
Process Optimization: During the production of Lapatinib, by monitoring the content of this impurity and analyzing its generation stage, it assists in optimizing the synthesis process, reducing the amount of impurity generation, and improving product quality.
Stability Studies: In drug stability tests, it analyzes the changes of this impurity under different storage conditions (such as temperature, humidity, light), providing key data support for determining the shelf life and storage conditions of drugs.
Background Description: Lapatinib is an important targeted drug for the treatment of HER2-positive breast cancer. In its research, development, production, and quality control, impurity research is the key to ensuring drug safety and effectiveness. The presence of impurities may affect the therapeutic effect of the drug and even pose potential risks. As a related impurity of Lapatinib, in-depth research on Lapatinib Impurity 8 helps to comprehensively evaluate the quality of Lapatinib drugs and ensure the safety and effectiveness of clinical medication.
Research Status: Currently, research on Lapatinib Impurity 8 continues to deepen. In terms of detection technology, advanced methods such as Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) and high-resolution mass spectrometry are continuously being explored to achieve precise detection of trace impurities. In the study of impurity generation mechanisms, the formation causes and influencing factors are deeply analyzed by simulating the drug synthesis reaction process and storage environment, providing a theoretical basis for controlling impurities from the source. At the same time, research on the impact of this impurity on the efficacy and safety of Lapatinib is also gradually being carried out, aiming to further improve the comprehensive understanding of the quality of Lapatinib drugs
NOTE！
We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com
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