Basic information Safety Related Supplier

ChemicalBook Product Catalog Levcromakalim

1/1

Levcromakalim NEW

$71.00 2mg

$101.00 5mg

$153.00 10mg

Min. Order
Purity99.91%
Cas No94535-50-9
Supply Ability10g
Update time2026-04-13

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP4Y

United States

United States

show more

Enterprise Verified

Business Bank account Basic Contact Infomation Business Address Trade Company

Chemical Properties

Product Name	Levcromakalim
CAS No	94535-50-9
EC-No
Min. Order
Purity	99.91%
Supply Ability	10g
Release date	2026/04/13

Product Introduction

Bioactivity

Name	Levcromakalim
Description	Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.
In vitro	Levcromakalim inhibits spontaneous contractions completely in a glibenclamide-sensitive manner. LevCromakalim (5 μM) inhibits spontaneous contractions, which are recovered by glibenclamide. Levcromakalim (1, 5 and 10 μM) inhibits phasic contractions to 34±21.1%, 20.1±20.0% and 0% of the control. Glibenclamide reverses the inhibition of spontaneous isometric contractions caused by LevCromakalim (5 μM) to 84±1.5% of the control. Levcromakalim (20 and 100 μM) also inhibits oxytocin (OXT) (10 nM)-induced phasic contractions to 34±21.4% and 14±12.6% of the control [2]. LevCromakalim induces dose-dependent relaxation in both the young and old mesenteric artery (MAs); there is no difference in relaxation with age. However, the relaxation is markedly reduced in response to the high-salt (HS) diet in the old MAs (P<0.05). Maximum dilations to Levcromakalim (10-4 M) are 97 ± 3% in the young MAs versus 98 ± 1% in the young salt arteries, while dilations are 99±0.7% in the old MAs when compared with 85 ± 5% in the old salt arteries (P<0.05) [3].
Storage	Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	H2O : Insoluble 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (6.98 mM), Sonication is recommended. DMSO : 50 mg/mL (174.62 mM), Sonication is recommended.
Keywords	PotassiumChannel \| Potassium Channel \| Levcromakalim \| KcsA \| Inhibitor \| inhibit \| Cromakalim \| BRL-38227 \| BRL38227 \| ATP-sensitive potassium (KATP) channels
Inhibitors Related	Minoxidil sulfate \| Tannic acid \| Hydrochlorothiazide \| 1,8-Cineole \| Tetraethylammonium bromide \| Ursodeoxycholic acid \| Chenodeoxycholic acid \| Minoxidil \| Chlorzoxazone \| 2,2,2-Trichloroethanol \| Taurocholic acid sodium salt hydrate \| Indapamide
Related Compound Libraries	Bioactive Compound Library \| Pain-Related Compound Library \| Membrane Protein-targeted Compound Library \| ReFRAME Related Library \| Neuroprotective Compound Library \| NO PAINS Compound Library \| Bioactive Compounds Library Max \| Covalent Inhibitor Library \| Potassium Channel Targeted Library \| Ion Channel Targeted Library \| Anti-Cancer Compound Library

show more

Company Profile Introduction

You may like

Recommended supplier

Send Inquriy