PRODUCT INFORMATION
| Common Name | Licochalcone A |
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| CAS Number | 58749-22-7 | Molecular Weight | 338.397 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 532.6±50.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O4 | Melting Point | 100° |
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| MSDS | N/A | Flash Point | 186.9±23.6 °C |
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Use of Licochalcone A
Licochalcone A, a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch, presents obvious anti-cancer effects. The IC50 value is 0.97 μM for UGT1A1. |
Names
| Name | (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one |
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| Synonym | More Synonyms |
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Licochalcone A Biological Activity
| Description | Licochalcone A, a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch, presents obvious anti-cancer effects. The IC50 value is 0.97 μM for UGT1A1. |
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| Related Catalog | Signaling Pathways >> Autophagy >> Autophagy Natural Products >> Flavonoids Research Areas >> Cancer |
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| References | [1]. Tang ZH, et al. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Sci Rep. 2016 May 17;6:26241. [2]. Hong Xin, et al. Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. Food and Chemical ToxicologyVolume 90, April 2016, Pages 112–122 [3]. Egler J, et al. Licochalcone A Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2015;37(5):2060-70. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 532.6±50.0 °C at 760 mmHg |
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| Melting Point | 100° |
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| Molecular Formula | C21H22O4 |
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| Molecular Weight | 338.397 |
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| Flash Point | 186.9±23.6 °C |
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| Exact Mass | 338.151794 |
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| PSA | 66.76000 |
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| LogP | 4.95 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.611 |
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| Storage condition | ?20°C |
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Safety Information
| Hazard Codes | Xn |
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| Risk Phrases | 20/21/22 |
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| Safety Phrases | 36/37 |
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| RTECS | UB8755000 |
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Synonyms
| (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one |
| Licochalcone A |
| (2E)-3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hdyroxyphenyl)-2-propen-1-one |
| LicochalconeA |
| LICOAGROCHACONE A |
| (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methyl-3-buten-2-yl)phenyl]-1-(4-hydroxyphenyl)-2-propen-1-one |
| 2-Propen-1-one,3-(5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)-,(E) |
| (2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one |
| Licochalcone-A,Synthetic |
| 5-(1,1-dimethylallyl)-4,4'-dihydroxy-2-methoxychalcone |
| (2E)-3-[5-(1,1-dimethylprop-2-en-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one |
| 3-Dimethylallyl-4,4'-dihydroxy-6-methoxychalcone |
| 2-Propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)- |
Company Profile
Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.
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