| Name | Liothyronine sodium |
| Description | Liothyronine Sodium is the sodium salt form of liothyronine, a synthetic form of the levorotatory isomer of the naturally occurring thyroid hormone triiodothyronine (T3). Liothyronine sodium (3,3',5-Triiodo-L-thyronine sodium) binds to nuclear thyroid receptors which then bind to thyroid hormone response elements of target genes. As a result, liothyronine sodium induces gene expression that is required for normal growth and development. Liothyronine sodium is more potent and has a more rapid action than thyroxine (T4). |
| In vivo | The chemical properties of Liothyronine Sodium are nearly identical to those of Triiodothyronine, acting on thyroid hormone receptors alpha and beta-1. As the most potent form of thyroid hormone, Liothyronine Sodium can increase the basal metabolic rate, affect protein synthesis, and enhance the body's sensitivity to catecholamines (such as adrenaline). |
| Storage | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 15 mg/mL (22.29 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (2.97 mM), Sonication is recommended.
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| Keywords | TRβ | TRα | Triiodothyronine | Thyroidhormonereceptor(THR) | Thyroidhormonereceptor | Thyroid hormone receptor(THR) | Thyroid Hormone Receptor | thyroid hormone | THR | T3 Sodium | T-3 | T 3 | Liothyronine sodium | Liothyronine | Inhibitor | inhibit | Endogenous Metabolite |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | DL-Lysine | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Pediatric Drug Library | Approved Drug Library | ReFRAME Related Library | Drug-induced Liver Injury (DILI) Compound Library | Toxic Compound Library | Drug Repurposing Compound Library | NO PAINS Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Human Metabolite Library |
United States
