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ChemicalBook Product Catalog Macimorelin acetate

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Macimorelin acetate NEW

$469.00 25mg

$673.00 50mg

Min. Order
Purity99.98%
Cas No945212-59-9
Supply Ability10g
Update time2026-04-14

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

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United States

United States

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Chemical Properties

Product Name	Macimorelin acetate
CAS No	945212-59-9
EC-No
Min. Order
Purity	99.98%
Supply Ability	10g
Release date	2026/04/14

Product Introduction

Bioactivity

Name	Macimorelin acetate
Description	Macimorelin acetate is an orally active agonist of the GHSR (Growth Hormone Secretagogue Receptor) and functions as a growth hormone (GH) secretagogue. As a ghrelin mimetic, it potently stimulates the release of endogenous growth hormone by binding to GHSR. Macimorelin acetate is clinically utilized as a diagnostic tool for Adult Growth Hormone Deficiency (AGHD) and is being investigated for the treatment of Cancer Anorexia-Cachexia Syndrome (CACS). Additionally, it has shown potential in neurological research for suppressing seizure activity.
In vitro	NFATc1-IN-1 (0、0.5、1.0、1.5、2.0、2.5 μM, 4 days) exhibits potent inhibitory activities on osteoclast formation and function, which eventually translates into decreased bone resorption while showing no cytotoxic effects towards osteoclast precursor cells at concentrations of as high as 2.5 μM.[1] NFATc1-IN-1 (1.5-2.5 μM, 24 h) blocks NFATc1 nuclear translocation and decreases the level of NFATc1.[1]
In vivo	Macimorelin acetate suppresses acute seizures in epileptic mice (5 mg/kg, i.p.) but lacks long-term antiepileptic effects [2]. Orally, it rapidly and dose-dependently increases GH levels, serving as an effective diagnostic for AGHD [1].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 80 mg/mL (149.64 mM), Sonication is recommended.
Keywords	UMV-1843 \| UMV1843 \| UMV 1843 \| Macrilen \| Macimorelin Acetate \| Macimorelin \| JMV-1843 \| JMV1843 \| JMV 1843 \| EP-1572 acetate ; AEZS-130 Acetate \| EP-1572 acetate ; AEZS130 Acetate \| EP-1572 acetate ; AEZS 130 Acetate \| EP-1572 acetate ; AEZS-130 acetate \| EP-1572 Acetate \| EP1572 Acetate \| EP-1572 \| EP1572 \| EP 1572 Acetate \| EP 1572 \| D-87575 acetate \| ARD-07 \| ARD07 \| AibDTrpDgTrpCHO. Macimorelin Acetate \| AEZS-130 Acetate \| AEZS130 Acetate \| AEZS-130 \| AEZS130 \| AEZS 130 Acetate \| AEZS 130
Inhibitors Related	Ibutamoren Mesylate \| YIL 781 \| AnaMorelin hydrochloride \| Anamorelin \| Ibutamoren \| CJC-1295 acetate(863288-34-0 free base) \| L-692429 \| Obestatin (human) \| Taurolithocholic Acid 3-sulfate (sodium salt) \| JMV 2959 hydrochloride (925238-89-7 free base) \| Obestatin (rat) acetate \| Cortistatin-8 acetate

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