| Name | Macranthoside A |
| Description | Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective activities, inhibits the production of pro-inflammatory cytokines and inhibits the activation of inflammatory signaling pathways, helps neutralize harmful free radicals, protects cells from oxidative damage, and promotes the survival and growth of neurons. And prevent neuronal cell death caused by oxidative stress or neurotoxic compounds, which has the potential to treat neurodegenerative diseases, cardiovascular diseases and liver damage. |
| In vitro | Macranthoside A was metabolized to kalopanaxsaponin A and I, hederagenin 3-O-alpha-L-arabinopyranoside and hederagenin. The main metabolites of Macranthoside A were kalopanaxsaponin I and hederagenin. Among kalopanaxsaponin B, H and their metabolites, kalopanaxsaponin A showed the most potent antidiabetic activity, followed by hederagenin. However, the main components, kalopanaxsaponin B and Macranthoside A, in K. pictus were inactive[1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Macranthoside A | Antioxidant |
| Inhibitors Related | Neomycin sulfate | Adipic dihydrazide | Levulinic acid | Kanamycin sulfate | D(+)-Raffinose pentahydrate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Hyaluronic acid sodium (MW 20 kDa) | Dimethyl sulfoxide | Sodium diacetate | BES |
| Related Compound Libraries | Terpene Natural Product Library | Traditional Chinese Medicine Monomer Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Saccharide and Glycoside Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Neuroprotective Compound Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max |
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