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ChemicalBook Product Catalog API Antineoplastic agents Alkylating antineoplastic Mizolastine

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Mizolastine NEW

$30.00 100mg

$98.00 500mg

Min. Order
Purity99.77%
Cas No108612-45-9
Supply Ability10g
Update time2025-04-27

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

VIP2Y

United States

United States

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Chemical Properties

Product Name	Mizolastine
CAS No	108612-45-9
EC-No
Min. Order
Purity	99.77%
Supply Ability	10g
Release date	2025/04/27

Product Introduction

Bioactivity

Name	Mizolastine
Description	Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives.
Kinase Assay	ssay for cytokines: The cultures for cytokine production are set up at 37 °C as follows: the mixtures of SN-4 and autologous APC (each 1 × 105 cells/well) are cultured for 3 days with 50 μg/mL of Cry j1 in a total volume of 0.2 mL in round-bottomed micro plates; PBMC (2 × 10 5 cells/well) from normal donors are cultured for 24 hours with 10 μg/ml of PHA in a total volume of 0.2 mL in flat-bottomed, 96-well micro plates; and purified T cells (1 × 105 cells/well) from normal donors are cultured in a total volume of 1 ml for 24 hours with anti-CD3 mAb that have been immobilized on flat-bottomed, 24-well plates at a concentration of 5 μg/ml. Cytokines in the culture supernatants are quantitatively assayed by the following commercially available kits: IL-4 and IFN-γ. The sensitivity of the assay is 30 pg/mL for IL-4 and 1 U/mL for IFN-γ.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 12 mg/mL (27.75 mM), Sonication is recommended.
Keywords	SL-850324 \| SL850324 \| second generation antihistamine \| Mizolastine \| mast cells \| Inhibitor \| inhibit \| HistamineReceptor \| Histamine Receptor \| H1 receptor \| chronic idiopathic urticarial \| allergic rhinitis
Inhibitors Related	Chlorphenesin \| Histamine dihydrochloride \| Meclizine dihydrochloride \| Mirtazapine \| Lidocaine \| Famotidine \| Mebhydrolin napadisylate \| Sodium butanoate \| Amitriptyline hydrochloride \| Alginic acid \| Trazodone hydrochloride \| Mianserin hydrochloride
Related Compound Libraries	Bioactive Compound Library \| Pain-Related Compound Library \| Anti-Neurodegenerative Disease Compound Library \| Membrane Protein-targeted Compound Library \| Anti-Cancer Clinical Compound Library \| Anti-Viral Compound Library \| Drug Repurposing Compound Library \| Inhibitor Library \| Anti-Cancer Approved Drug Library \| Bioactive Compounds Library Max \| GPCR Compound Library \| Anti-Cancer Drug Library

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