Technical Data Sheet (TDS)
Product Name: Monoammonium Glycyrrhizinate
Synonyms: Glycyrrhizic Acid Monoammonium Salt, Glycyrrhizin Ammonium Salt
CAS No.: 53956-04-0
Molecular Formula: C₄₂H₆₂O₁₆·NH₄
Molecular Weight: ~839.0 g/mol
Source: Extracted from the roots of Glycyrrhiza glabra (Licorice)
1. Product Description
Monoammonium Glycyrrhizinate is the ammonium salt of glycyrrhizic acid, a natural triterpenoid saponin glycoside obtained from licorice root. It has an intensely sweet taste (approximately 50–100 times sweeter than sucrose) and exhibits biological activities including anti-inflammatory, antioxidant, and emulsifying properties. Widely used in food, beverages, cosmetics, pharmaceuticals, and industrial formulations.
2. Specifications
| Item | Specification | Test Method |
|---|
| Appearance | White to yellowish powder | Visual |
| Odor & Taste | Characteristic, intensely sweet | Sensory |
| Identification | Positive (HPLC/IR) | USP/EP |
| Assay (HPLC, dry basis) | ≥ 98% | HPLC |
| Solubility | Freely soluble in water; insoluble in ethanol | Test in water |
| Loss on Drying | ≤ 5.0% | USP |
| Ash | ≤ 0.5% | USP |
| pH (1% solution) | 4.5 – 6.5 | pH meter |
| Heavy Metals | ≤ 10 ppm | ICP-MS |
| Lead (Pb) | ≤ 2 ppm | ICP-MS |
| Arsenic (As) | ≤ 1 ppm | ICP-MS |
| Cadmium (Cd) | ≤ 1 ppm | ICP-MS |
| Mercury (Hg) | ≤ 0.1 ppm | ICP-MS |
| Microbiological Limits |
|
|
| Total Plate Count | ≤ 1,000 CFU/g | USP |
| Yeast & Mold | ≤ 100 CFU/g | USP |
| E. coli / Salmonella | Negative | USP |
3. Applications
Food & Beverage Industry
Natural sweetener (50–100 times sweeter than sucrose, low calories).
Flavor enhancer in soft drinks, candies, and bakery.
Foaming & emulsifying agent in beverages.
Functional additive for anti-oxidation and liver protection.
Industrial / Pharmaceutical / Cosmetic
Pharmaceutical excipient: expectorant, anti-inflammatory, hepatoprotective.
Cosmetics: skin-soothing agent, anti-irritant, used in creams, lotions, and sunscreens.
Tobacco industry: used as flavoring and humectant.
Industrial use: foaming agent in detergents and emulsions.
4. Packaging & Storage
Pckaging: 1kg/Aluminum foil bag; 25kg/Drum (fiber drum with inner double PE bag).
Storage: Store in a cool, dry, and well-ventilated place, away from strong light and heat.
Shelf Life: 24 months under proper storage conditions.
5. Safety & Regulatory Information
Food Grade Status: GRAS (Generally Recognized As Safe) when used in accordance with FDA guidelines.
Allergen Status: Allergen-free.
Non-GMO, Non-irradiated.
Handling: Avoid dust inhalation; use protective gloves and eyewear during handling.
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