1. Materials information
Use of BTS
BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uMTarget: Ca2+-stimulated myosin S1 ATPaseBTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II.
| Name | N-benzyl-4-methylbenzenesulfonamide |
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| Synonym | More Synonyms |
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BTS Biological Activity
| Description | BTS is a potent inhibitor of Ca2+-stimulated myosin S1 ATPase (IC50 ~ 5 μM) and reversibly blocks the gliding motility. IC50 value: 5 uMTarget: Ca2+-stimulated myosin S1 ATPaseBTS also weakens myosin’s interaction with F-actin. BTS is much less effective in suppressing contraction in rat myocardial or rabbit slow twitch muscle and has no effect on platelet myosin II. |
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| Related Catalog | Signaling Pathways >> Cytoskeleton >> Myosin Research Areas >> Cancer |
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| References | [1]. Cheung A, et al. A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol. 2002 Jan;4(1):83-8. |
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Chemical & Physical Properties
| Density | 1.204 g/cm3 |
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| Boiling Point | 419.1ºC at 760 mmHg |
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| Melting Point | 115 °C |
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| Molecular Formula | C14H15NO2S |
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| Molecular Weight | 261.33900 |
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| Flash Point | 207.3ºC |
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| Exact Mass | 261.08200 |
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| PSA | 54.55000 |
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| LogP | 3.94520 |
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| Vapour Pressure | 3.12E-07mmHg at 25°C |
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| Index of Refraction | 1.589 |
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| Storage condition | Desiccate at RT |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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