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ChemicalBook Product Catalog N-hexadecanoyl-L-Homoserine lactone

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N-hexadecanoyl-L-Homoserine lactone NEW

$95.00 5mg

$178.00 10mg

$730.00 50mg

Min. Order
Purity
Cas No87206-01-7
Supply Ability10g
Update time2026-04-13

TargetMol Chemicals Inc.

TargetMol Chemicals Inc.

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United States

United States

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Chemical Properties

Product Name	N-hexadecanoyl-L-Homoserine lactone
CAS No	87206-01-7
EC-No
Min. Order
Purity
Supply Ability	10g
Release date	2026/04/13

Product Introduction

Bioactivity

Name	N-hexadecanoyl-L-Homoserine lactone
Description	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density.[1] This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production.[2] Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases.[3] AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family.[4] C16-HSL is one of a number of lipophilic, long acyl side-chain bearing AHLs, including its monounsaturated analog C16:1-(L)-HSL, produced by the LuxI AHL synthase homolog SinI involved in quorum-sensing signaling in S. meliloti, a nitrogen-fixing bacterial symbiont of certain legumes.[5],[6] C16-HSL is the most abundant AHL produced by the proteobacterium R. capsulatus and activates genetic exchange between R. capsulatus cells.[7] N-Hexadecanoyl-L-homoserine lactone and other hydrophobic AHLs tend to localize in relatively lipophilic cellular environments of bacteria and cannot diffuse freely through the cell membrane. The long-chain N-acylhomoserine lactones may be exported from cells by efflux pumps or may be transported between communicating cells by way of extracellular outer membrane vesicles.[8],[9]
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	Chloroform : 1 mg/mL (2.95 mM), Sonication is recommended.
Keywords	NhexadecanoylLHomoserine lactone \| N hexadecanoyl L Homoserine lactone

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