| Name | N-Nitrosodiethylamine |
| Description | N-Nitrosodiethylamine (NDEA) is a carcinogenic dialkylnitrosamine commonly found in water, tobacco smoke, cheddar cheese, pickled foods, fried foods, and various alcoholic beverages; it is associated with alterations in nucleases involved in DNA repair and replication, targets organs such as the nasal cavity, trachea, lungs, esophagus, and liver to induce tumors in animals, and is most commonly used to induce liver cancer models. |
| In vivo | Mice with N-Nitrosodiethylamine (25mg/kg) intraperitonially resulted in fatty liver disease leading to progress of cancer disease. |
| Storage | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (19.58 mM), Sonication is recommended. PBS : 100 mg/mL (979.05 mM) H2O : 98 mg/mL (959.47 mM), Sonication is recommended. DMSO : 50 mg/mL (489.52 mM), Sonication is recommended.
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| Keywords | RNASynthesis | RNA Synthesis | N-Nitrosodiethylamine | NNitrosodiethylamine | N Nitrosodiethylamine | Inhibitor | inhibit | DNASynthesis | DNA/RNA Synthesis | DNA Synthesis |
| Inhibitors Related | 5-Fluorouracil | Adenine hemisulfate | Erythromycin thiocyanate | Guanidine hydrochloride | Hexane-1,6-diol | 1,4-Naphthoquinone | Adenine | Vidarabine | Carbazole | Thymidine | Docosanoic acid | Usnic Acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Natural Product Library | Tobacco Monomer Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |